Table 1.
Single-Channel properties in the presence of 50 μm GABA and various concentrations of ethaol
| Ethanol | OT1 | OT2 | OT3 | CT1 | CT2 | CTβ | ||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| (%) | (ms) | (%) | (ms) | (%) | (ms) | (%) | (ms) | (%) | (ms) | (%) | (ms) | (%) |
| 0 | 0.3 ± 0.1 | 26 ± 1 | 3.0 ± 0.3 | 58 ± 6 | 7.1 ± 0.9 | 16 ± 6 | 0.2 ± 0.1 | 64 ± 1 | 1.6 ± 0.1 | 16 ± 1 | 21.2 ± 0.5 | 21 ± 1 |
| 0.1 | 0.4 ± 0.1 | 31 ± 3 | 3.8 ± 0.6 | 57 ± 12 | 8.2 ± 2.8 | 12 ± 13 | 0.2 ± 0.1 | 54 ± 3 | 1.5 ± 0.4 | 15 ± 2 | 16.9 ± 2.6 | 30 ± 2 |
| 0.5 | 0.3 ± 0.1 | 18 ± 2 | 1.7 ± 0.1 | 57 ± 3 | 5.7 ± 0.3 | 24 ± 3 | 0.2 ± 0.1 | 59 ± 1 | 1.4 ± 0.1 | 27 ± 1 | 13.2 ± 0.5 | 14 ± 1 |
| 2 | 0.2 ± 0.1 | 21 ± 3 | 2.4 ± 0.3 | 59 ± 13 | 4.6 ± 1.4 | 20 ± 24 | 0.1 ± 0.1 | 54 ± 3 | 1.4 ± 0.3 | 24 ± 2 | 11.0 ± 1 | 23 ± 3 |
The intracluster open and closed time histograms were fitted using program MIL. Error limits were calculated as described in Methods. In the absence of ethanol, the dataset contained 3 patches (total of 10 949 events). In the presence of ethanol, the datasets (one patch at each ethanol concentration) contained 2352 events (0.1%), 14 541 events (0.5%) or 2268 events (2% ethanol).