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. 2002 Dec 6;546(Pt 3):641–646. doi: 10.1113/jphysiol.2002.032300

Figure 1. Coapplication of ethanol and ACN increases cluster open probability.

Figure 1

Single-channel clusters obtained in the presence of 50 µm GABA and in the absence or presence of 0.1 % ethanol, 10 nm ACN, 0.1 % ethanol + 10 nm ACN or 1 µm ACN. Channel openings are shown downward. The intracluster closed and open time histograms for each set of conditions are given next to the representative cluster. In the presence of GABA and 1 µm ACN, the mean closed durations were 0.12 (67 %), 1.1 (17 %), 21.2 (11 %) and 91 ms (5 %). The mean open durations were 0.42 (26 %), 3.4 (33 %) and 27.8 (42 %). For other sets of data, the parameters of the fit are given in Tables 1 and 2.