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. 2008 Apr 2;105(14):5614–5619. doi: 10.1073/pnas.0801689105

Fig. 2.

Fig. 2.

Reduced brain size and weight in Dcr flox/flox;DR-1 Cre mice. (A) A representative brain from a control Dcr flox/wt; DR-1 Cre mouse (Left) as compared with a brain from a Dcr flox/flox; DR-1 Cre animal (Right) (littermates, 10 weeks old). (B) Brain weights of dying Dcr flox/flox; DR-1 Cre animals (empty bars) and controls (filled bars) from males (n = 7) and females (n = 6). Student's t test, ***, P = 0.0004 and 0.0007, respectively, SEM is shown. Brains were obtained from animals between 10 and 12 weeks of age.