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BAG956 represses the PI3-K/AKT pathway in leukemia cells. (A,B) Treatment of Ba/F3.p210 cells for 2 hours with a range of concentrations of BAG956. (C) Treatment of Ba/F3.p210 cells for 0 to 12 hours with 200 nM BAG956. (D) Treatment of MOLM14 cells for 0 to 13 hours with 250 nM BAG956. (E) Treatment of MOLM14 cells for 2 hours with BAG956 alone, rapamycin alone, or a combination of BAG956 and rapamycin.
