TABLE 5.
Replication of b/h PIV3 expressing hMPV F protein at position 1 or 2 of the PIV3 genome in hamsters
| Virusa | Mean virus titer on day 4 postinfection (log10 TCID50/g of tissue ± SE)b
|
|
|---|---|---|
| Nasal turbinates | Lungs | |
| b/h PIV3 | 4.8 ± 0.2 | 5.6 ± 0.6 |
| b/h hMPV F1 | 5.3 ± 0.5 | 5.7 ± 0.4 |
| b/h hMPV F2 | 5.7 ± 0.5 | 4.6 ± 0.3 |
| hMPV | 5.3 ± 0.1 | 3.6 ± 0.3 |
a
Groups of six hamsters were inoculated intranasally with 106 PFU of the virus indicated.
b
TCID50 assays were read for CPE on day 10 postinfection. SE, standard error.