Figure 3.
Linear regression for prediction of the ribozyme activity (as measured by (1-Su3600) for the amount of substrate cleaved at 1 hr) for 13 "normally behaving" ribozymes. (A) For ΔGdisruption as the predictor, the R2 for the regression is 0.4677, and the P-value is 0.0099. (B) For ΔGtotal as the predictor, the R2 for the regression is 0.6242, and the P-value is 0.0013. Also plotted are the two outliers (GUC11 and GUC3) that were not included in the regression analysis (see Results, Figures 4 and 5 for explanations of the outliers).