Table 4.
TRAIL receptor-2 mRNA expression
| Case | Lymphochip 1 | Lymphochip 2 | RT-PCR 1 | RT-PCR 2 |
|---|---|---|---|---|
| Mutated 1 | 0.39 | 0.43 | 0.59 | 0.61 |
| Mutated 2 | 0.46 | 0.5 | 0.28 | 0.56 |
| Mutated 3 | 0.54 | 0.48 | 0.12 | 0.16 |
| Mean (± SD)* | 0.46 (± 0.08) | 0.47 (± 0.04) | 0.33 (± 0.24) | 0.44 (± 0.25) |
| Wild-type 1 | 1.49 | 1.53 | 2.72 | 3.44 |
| Wild-type 2 | 1.53 | 1.55 | 0.84 | 1.02 |
| Wild-type 3 | 1.63 | 2 | 1.54 | 2.07 |
| Mean (± SD)* | 1.55 (± 0.07) | 1.69 (± 0.27) | 1.70 (± 0.95) | 2.18 (± 1.21) |
Lymphochip 1 and 2 represent relative mRNA expression data compared to control mRNA of pooled cell lines from 2 probes in Rosenwald et al.11 RT-PCR 1 and RT-PCR 2 represent relative copy number compared with GAPDH using 2 different probes.
*
Mean (± SD) of 3 cases.