Table I.
Parameters of the Voltage Dependence of Activation
| Channel | v1/2 * | zm (e0)* | n * | |||
|---|---|---|---|---|---|---|
| mV | ||||||
| IFMQ3 | −29.1 ± 2.7 | 5.1 ± 1.1 | 10 | |||
| 1R2Q | −30.1 ± 1.6 | 5.5 ± 0.6 | 4 | |||
| 1R2K | −26.3 ± 1.7 | 4.6 ± 0.5 | 3 | |||
| 1K4Q | −10.6 ± 3.5‡ | 3.9 ± 0.6‡ | 7 | |||
| 1K4R | −25.3 ± 2.5‡ | 5.1 ± 0.3 | 7 | |||
| 2R2Q | −24.7 ± 1.5‡ | 4.0 ± 0.8‡ | 7 | |||
| 2R2K | −20.0 ± 1.8‡ | 4.2 ± 0.5 | 4 | |||
| 2K4Q | −14.2 ± 3.1‡ | 4.4 ± 0.9 | 5 | |||
| 2K4R | −25.3 ± 1.0‡ | 4.9 ± 1.3 | 5 | |||
| 3R2Q | −29.4 ± 1.9 | 5.5 ± 0.4 | 5 | |||
| 3R2K | −29.5 ± 5.2 | 5.5 ± 0.5‡ | 4 | |||
| 3R4Q | −47.2 ± 6.4‡ | 5.4 ± 1.6 | 5 | |||
| 3R4K | −19.3 ± 3.3‡ | 4.5 ± 0.9 | 8 | |||
| 4R2Q | −25.5 ± 1.7‡ | 4.6 ± 0.4 | 5 | |||
| 4R2K | −25.0 ± 1.7‡ | 5.1 ± 0.4 | 3 | |||
| 4R4Q | −28.7 ± 1.6 | 6.0 ± 0.8 | 7 | |||
| 4R4K | −21.7 ± 1.5‡ | 5.7 ± 0.3 | 5 | |||
| 1K4Q:2K4Q | −12.2 ± 1.4‡ | 2.6 ± 0.2‡ | 7 | |||
| 3R4Q:4R4Q | −39.4 ± 1.7‡ | 4.5 ± 0.9 | 6 |
v1/2 and zm are the half-maximal voltage and gating valence of activation as determined by least-squares fits of the data (n = number of separate determinations) to a two-state Boltzmann function as described in materials and methods.
Values significantly different from IFMQ3, with a probability <0.05 resulting from random variation (based on Student's unpaired t test).