FIG. 4.
Prediction of MAb NTs required for protection. (A) Estimated MAb NTs against the autologous viruses required to achieve 50% protection among responding patients according to the method of Reed and Muench (15, 22). The gray shaded area represents the threshold of MAb NT activity required to achieve a 50% proportion of responders. (B) Analysis as described for panel A of a patient cohort subgrouped into acute and chronic individuals. Blue and green shaded areas represent the thresholds of MAb NT activity required to achieve a 50% proportion of responders among acute and chronic individuals, respectively.