Fig. 2.
Development of a library of ESPers making use of the solvent effect on PeT. (a) Structures of 2I-BDP derivatives with various benzene moieties. (b) Relationship between the relative efficiency of 1O2 generation (φΔ) of 2I-BDP derivatives (1a–1f) and the dielectric constant of the solvent. Solvents used in this study were CH3CN, MeOH, acetone, CH2Cl2, and CHCl3, whose dielectric constants are 37.5, 33.6, 20.7, 9.14, and 4.81, respectively. Filled blue circle, 1a; open blue circle, 1b; green star, 1c; open green square, 1d; open green diamond, 1e; red star, 1f. (c) Structures of ESPer 1c-conjugated IP3 derivatives and control (Con) photosensitizer 1b-conjugated IP3 derivatives; d- and l- refer to the d and l absolute configurations of inositol 1,4,5-trisphosphate.