Table I.
Four Distinct Outward K+ Currents in Mouse Ventricular Myocytes
| Cells | Ipeak | Ito,f | Ito,s | IK,slow | Iss | |||||
|---|---|---|---|---|---|---|---|---|---|---|
| With Ito | ||||||||||
| τdecay (ms) | — | 85 ± 2 | — | 1162 ± 29 | — | |||||
| Density* (pA/pF) | 47.0 ± 2.5 | 26.2 ± 1.6 | — | 14.9 ± 0.9 | 5.5 ± 0.3 | |||||
| Percent Ipeak | — | 56 | — | 32 | 12 | |||||
| n | 65 | 65 | — | 65 | 65 | |||||
| Without Ito,f | ||||||||||
| τdecay (ms) | — | — | 196 ± 7 | 1368 ± 101 | NA | |||||
| Density* (pA/pF) | 31.5 ± 4.1 | — | 11.4 ± 1.9 | 15.6 ± 2.1 | 4.5 ± 0.5 | |||||
| Percent Ipeak | — | — | 36 | 50 | 14 | |||||
| n | 7 | — | 7 | 7 | 7 |
*
Current densities were determined from analyses of records obtained on depolarization to +40 mV from a holding potential of −70 mV; all values are means ± SEM.