Figure 2.
CD5 surface expression on thymocytes from Rag-2−/− and TCR-α−/− mice. Dot plots illustrate the CD4/CD8 staining profile and demonstrate the stage at which thymocyte development is blocked. Histograms depict CD5 and CD3 surface levels on gated CD4−CD8− (DN) thymocytes (A), or CD4+CD8+ (DP) thymocytes (B). CD5 and CD3 surface expression on DN and DP thymocytes from control (WT) animals are included for comparison. Dotted lines represent control peaks.
