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. 2004 Oct 18;200(8):1015–1026. doi: 10.1084/jem.20040581

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Copyright © 2004, The Rockefeller University Press

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Figure 2. — Absence of any effect of Aire mutation on insHEL expression in the β islets and serum. HEL protein concentration in the serum of 6–12-wk-old insHEL transgenic mice of the indicated Aire genotypes, and surface expression of HEL protein on pancreatic islet cells. HEL surface staining of insHEL transgenic islet is shown in gray, and background control staining of nontransgenic B10.Br islets is shown in white (representative histogram, n = 2).