Fig. 2.
Distinct (co)expression patterns of TRAs in individual MECs and mTECs. Each row represents a single cell analyzed for expression of the genes listed above the columns; ticks indicate 10-cell intervals. Black denotes detected expression, gray lack of expression, and white expression not analyzed. Expression patterns were arranged from top to bottom according to increasing number of genes expressed per cell. (A) Expression pattern of mature MECs. Note the high number of cells coexpressing MEC specific genes including the transcription factor Elf5 and its regulated gene WAP. (B) CD80hi mTECs exhibit either expression of single genes or a varied selection of MEC-specific genes. Contiguous expression of the casein locus was found in only one cell (bottom row).