Figure 2.
Macrophage recruitment defect in ccr2 −/− mice. Resident and thioglycollate-elicited (72 h post-i.p. injection) peritoneal cells were lavaged from groups of wild-type (open bars) and ccr2 −/− (black bars) mice. Macrophage (Mac), eosinophil (Eos), and neutrophil (Neut) cell numbers were determined from total cell numbers after differential staining with Diff-Quik. For resident cell counts, values represent mean ± SEM of 5 wild-type or ccr2 −/− mice. For elicited cell counts, values represent mean ± SEM of 11 wild-type or ccr2 −/− mice. * P <0.05, ** P <0.006, ***P <0.00001; probabilities were determined by the unpaired Student's t-test.