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. 2001 Sep 17;194(6):833–846. doi: 10.1084/jem.194.6.833

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© 2001 The Rockefeller University Press

This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/).

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Antigenicity of analogs from three additional epitopes of tumor and viral antigens. IFN-γ production by CTLs specific for MAGEA2.157 (A), HBV Pol.455 (B), and HIV Pol.476 (C) in response to analogue-pulsed or wild-type (WT)-pulsed .221A2.1 cells is shown. The dotted line at each position demarcates the groups of five analogs with conservative/semiconservative substitutions (left of the line) and nonconservative substitutions (right of the line). Background IFN-γ responses were <25 pg/well.