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. 1999 Jul 1;190(1):65–74. doi: 10.1084/jem.190.1.65

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© 1999 The Rockefeller University Press

This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/).

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Capacity of cytokines to inhibit Fas-independent apoptosis of thymocyte subsets in vitro. Purified CD4⁺8⁺ or HSA^hiCD4⁺8⁻ thymocytes from normal B6 mice were cultured overnight either in medium alone (gray bars) or with a mixture of anti-TCR (0.1 μg/ml) and anti-CD28 mAbs (black bars); where indicated, the recombinant cytokines shown were added to the cultures at 100 U/ml. The data show mean percent apoptosis (top panels) and percent difference in (Δ) apoptosis (bottom panels).