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. 2003 Oct 20;198(8):1201–1212. doi: 10.1084/jem.20030305

Figure 3.

Figure 3.

Differentially expressed genes in dNK and pNK cells. Fold changes of genes that showed greater than or equal to threefold change. P ≤ 0.001 (black bars) in at least one of the three pairwise comparisons: dNK versus pNKbright (left diagrams); dNK versus pNKdim (middle diagrams); and pNKbright versus pNKdim (right diagrams) are presented. The 278 transcripts that met these criteria were classified into the following 10 categories: I, surface molecules/receptors/adhesion (A, 58 genes); II, chemokines/cytokines/immunomodulatory and other secreted proteins (B, 12 genes); III, immune effector molecules and apoptosis related (C, 7 genes); IV, signal transduction related (32 genes); V, cytoskeleton related (26 genes); VI, cell cycle + stress (15 genes); VII, DNA- binding/transcription/translation (33 genes); VIII, metabolism (23 genes); IX, other genes (40 genes); and X, genes with unknown function (33 genes). The first three categories are shown in this figure (A–C); data for the remaining categories are shown as Fig. S1. Black and gray bars represent fold changes in pairwise comparisons with significance levels ≥0.001 and ≤0.05, respectively. White bars represent statistically nonsignificant changes. Gene, gene name, or gene symbol obtained from Locuslink or Netaffx (Affymetrix, Inc.). GB, GenBank accession number. Probe ID, Affymetrix probeset designation. P-(Presence) calls (dNK, bright, and dim), number of present calls by Affymetrix algorithms in nine dNK, five pNK CD56bright, and five CD56dim NK cells, respectively.