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Impact of IFN Functions on IFN-α Production by DCs
| Strain | n a | IFN-α (pg/ml)
|
|
|---|---|---|---|
| Serab | DC CMc | ||
| IFN-α/βR+/+ | 4 | 382,270 ± 11,607 | 40,870 |
| IFN-α/βR−/− | 4 | 99,430 ± 14,181d | 12,390 |
Mice were infected intraperitoneally for 1.5 d with 104 PFUs MCMV.
Data are from one representative experiment out of three.
Number of mice per group.
Mean ± standard error.
24-h CM from enriched DCs.
P < 0.001.
