Abstract
In mice, thymectomized as young adults, neonatally induced tolerance persists in the putative absence of cell chimerism. The finding provides evidence that a selective deficiency of specific clones of lymphocytes exists in transplantation tolerance when induced under the conditions of these experiments.
Full Text
The Full Text of this article is available as a PDF (267.6 KB).
Selected References
These references are in PubMed. This may not be the complete list of references from this article.
- Bansal S. C., Hellström I., Hellström K. E., Wright P. W. Cell-mediated immunity and blocking serum activity before and after breakage of allograft tolerance in rats. Transplantation. 1973 Dec;16(6):610–620. doi: 10.1097/00007890-197312000-00013. [DOI] [PubMed] [Google Scholar]
- Droege W., Mayor K. Graft-versus-host reactivity and inhibitory serum factors in allograft-tolerant chickens. Transplantation. 1975 Jun;19(6):517–520. [PubMed] [Google Scholar]
- Elkins W. L. Deficit of specific thymus-dependent lymphocytes in transplantation tolerance in the rat. J Exp Med. 1973 Apr 1;137(4):1097–1102. doi: 10.1084/jem.137.4.1097. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Law L. W., Appella E., Strober S., Wright P. W., Fischetti T. Soluble transplantation antigens. Further studies of their tolerogenic properties. Transplantation. 1974 Dec;18(6):487–495. doi: 10.1097/00007890-197412000-00003. [DOI] [PubMed] [Google Scholar]
- Lubaroff D. M., Silvers W. K. Importance of chimerism in maintaining tolerance of skin allografts in mice. J Immunol. 1973 Jul;111(1):65–71. [PubMed] [Google Scholar]
- Miller J. F. Effect of thymectomy in adult mice on immunological responsiveness. Nature. 1965 Dec 25;208(5017):1337–1338. doi: 10.1038/2081337a0. [DOI] [PubMed] [Google Scholar]
- SJODIN K., DALMASSO A. P., SMITH J. M., MARTINEZ C. THYMECTOMY IN NEWBORN AND ADULT MICE. Transplantation. 1963 Oct;1:521–525. doi: 10.1097/00007890-196301040-00011. [DOI] [PubMed] [Google Scholar]
- Voisin G. A. Immunity and tolerance: a unified concept. Cell Immunol. 1971 Dec;2(6):670–689. doi: 10.1016/0008-8749(71)90014-1. [DOI] [PubMed] [Google Scholar]