Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2003 Nov 10;163(3):469–475. doi: 10.1083/jcb.200307035

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2003, The Rockefeller University Press

This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/).

PMC Copyright notice

Figure 2. — Histological and echocardiographic analysis of hearts from adult HB^uc/uc mice. (A and B) Hematoxylin-eosin staining of transverse sections through hearts of 12-wk-old mice at the papillary muscle level. Bar, 3 mm. (C and D) High magnification pictures. Sections were stained with Azan-Mallory. Massive fibrosis (blue stain) is present in 12-wk-old HB^uc/uc heart throughout the vessel wall. Bar, 250 μm. (E and F) Echocardiographic analyses of hearts from WT (+/+) and HB^uc/uc (uc/uc) mice. (E) Representative images of M-mode analyses are shown. Arrows indicate end-diastolic (d) and end-systolic (s) dimensions, respectively. (F) Physiological parameters of WT versus HB^uc/uc hearts in 12-wk-old mice. HR, heart rate; sBP and dBP, systolic and diastolic blood pressure; LVDd and LVDs, left ventricular end diastolic and end systolic internal dimensions; FS, percent fractional shortening calculated as [(LVDd − LVDs)/LVDd] × 100. All values ± SEM.