Figure 2.
The α3β1 integrin contributes to pulmonary arrest in rat lung. (a) Pulmonary attachment by ESb cells (+/+), ESb cells without either β1 integrin allele (−/−), or deficient cells reengineered to express β1a integrin (−/− + β1A). (b) Pulmonary attachment by MK1.16 (+/+), MK5.4.6 (−/−) cell without either α3 integrin, or deficient cells reengineered to express α3 (−/− + α3). (c) Pulmonary arrest of K562 parental cells compared with K562 expressing α3 or α6 integrin subunits.
