Figure 4.

Activated R-Ras enhances adhesion to collagen but not fibronectin. (A) Cells expressing activated R-Ras(87L) (triangles) are more adherent to collagen I than control cells expressing vector alone (open squares). In contrast, cells expressing dominant negative R-Ras(41A) (filled squares) are less adherent to collagen I. (b) Cells expressing activated or dominant negative R-Ras are no different from control cells in their adhesion to fibronectin. Values in a and b are an average of two separate experiments, each of triplet determinations, ± SD.