Figure 4.
The absence of dll4 alters the number and activation of T cells in the lung and lymph nodes of RSV-infected mice. Flow cytometry was performed using whole-lung digests or dispersed lymph nodes taken from mice 8 d after RSV infection. (A) The total number of CD4+ T cells in the lung and lymph node. *, P = 0.0134 for lung and 0.0042 for lymph node. (B) The number of CD4+CD69+ T cells in the lung and lymph node. *, P = 0.0065 for lung and 0.0020 for lymph node. (C) The total number of CD8+ T cells in the lung and lymph node. *, P = 0.0349 for lung and 0.0113 for lymph node. (D) The number of CD8+perforin+ cells in the lung and lymph node. *, P = 0.02. Error bars represent the mean ± the SEM.
