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The Mps3 N terminus is able to rescue the silencing defect of mps3Δ75–150 mutants. A 2-μm plasmid containing no insert, MPS3, mps3 1–75, mps3 1–150, or mps3 1–181 was transformed into the mps3Δ75–150 mutant (SLJ2516), and silencing at telomere V-R, HMR, and the rDNA was assayed as described in Fig. 7.
