Skip to main content
. Author manuscript; available in PMC: 2007 Nov 9.
Published in final edited form as: J Biol Chem. 2005 Aug 29;280(45):37747–37754. doi: 10.1074/jbc.M507464200

FIGURE 2. AR-mediated transcriptional activation by DHT, R-bicalutamide (R-bic), S-1, HF, and R-3 in the WT (a), T877A (b), W741L (c), and M895T (d) AR variants.

FIGURE 2

Relative luciferase units (RLU) normalized with β-galactosidase (β-gal) activity. Inter-experiment variation was observed with RLU/β-galactosidase values due to transfection efficiency, but relative drug-induced transcriptional activation was found consistent and therefore more accurately represents changes in functional activity observed in AR mutations.