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TEM of caveolae immunogold labeled for myc-tagged caveolin. Freshly isolated adipocytes were transfected with C-terminally myc-tagged caveolin-1 (A) or -2 (B). Plasma membrane sheets attached to grids were prepared and immunogold-labeled against the myc-tag, cryosputtered, and examined by TEM. Images have been contrast inverted.
