Table 2.

Effects of various PUFA, given with a control diet (Table 2A) or a UMP-supplemented diet (Table 2B), on gerbil brain phosphatide levels. Data are presented as nmol/mg protein.

Table 2A	Total PL	PC	PE	PS	PI
Control diet + Vehicle	322 ± 3	113 ± 3	63 ± 3	25 ± 1	15 ± 1
Control diet + AA	326 ± 5	114 ± 1	65 ± 2	28 ± 1	16 ± 1
Control diet + DHA	344 ± 13	133 ± 6^*	77 ± 4^*	32 ± 2^***	18 ± 1^*
Control diet + EPA	347 ± 6	125 ± 8	76 ± 4^*	31 ± 1^**	19 ± 1^**, ^a
^#UMP diet + Vehicle	332 ± 7	131 ± 2^*	70 ± 1	29 ± 1^*	16 ± 1
Table 2B	Total PL	PC	PE	PS	PI
UMP diet + Vehicle	332 ± 7	131 ± 2	70 ± 1	29 ± 1	16 ± 1
UMP diet + AA	379 ± 21	132 ± 3	81 ± 6	31 ± 3	20 ± 2
UMP diet + DHA	384 ± 7^*	147 ± 3^**, ^y	88 ± 2^**	39 ± 2^**	22 ± 1^**
UMP diet + EPA	407 ± 7^***	148 ± 2^**, ^y	91 ± 1^***	41 ± 2^**, ^x	25 ± 1^***

Groups of gerbils were given a control diet, and received by gavage AA, DHA, or EPA (each 300 mg/kg; in a vehicle of 5% gum Arabic solution) or just its vehicle for 28 days.

Groups of gerbils were given a UMP-containing (0.5%) diet, and received by gavage AA, DHA, or EPA (each 300 mg/kg; in a vehicle of 5% gum Arabic solution) or just its vehicle for 28 days.

On the 29th day their brains were harvested and assayed for phosphatides as described in the text. Data are given as means ± SEM.

P<0.05

^**

P<0.01

^***

P<0.001 compared to Control diet + Vehicle group

P<0.05 compared to Control diet + AA group by One Way ANOVA.

Data from gerbils receiving the UMP diet but no PUFA are included in Table 2A to illustrate that uridine alone also affects phosphatide levels.

P<0.05

P<0.01 compared to UMP diet + AA group by One Way ANOVA.