. 2007 Oct 17;104(43):17093–17098. doi: 10.1073/pnas.0707938104

Table 1.

Ability of HOXB13 to enhance growth of tumors with defined genetic alterations

Mouse ovarian cancer cell line	Genetic alterations	No. of tumors in which V(HOXB13)/V(GFP) > 2	Days between injection and tumor isolation^*
T1	p53^−/−, myc, K-ras	30/30	9–15^*
T11	p53^−/−, myc, K-ras	4/4	19^*
T2	p53^−/−, Akt, myc	0/10	20–55
T22	p53^−/−, Akt, myc	0/4	16–27
T22+ pBabe	p53^−/−, Akt, myc	0/10	14
T22+K-ras	p53^−/−, Akt, myc, K-ras	10/12	14^*
T22+H-ras	p53^−/−, Akt, myc, H-ras	3/3	8^*

V, volume.

*Mice were killed when tumor size on one or both flanks exceeded 1.4 cm³.