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Backbone RMSDs of double-layered Aβ models with (a) CC interfaces and (b) NN interfaces for both wild-type and mutants (E22G, E22Q, E22K, and M35A). The RMSD curves are shown for all residues (black line), β-sheet 1 residues (red line), β-sheet 2 residues (green line), loop1 residues (blue line), and loop2 residues (light-blue line).
