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. 1998 Mar 17;95(6):3100–3105. doi: 10.1073/pnas.95.6.3100

Figure 2.

Figure 2

Thrombin, collagen, U46619, and arachidonic acid-induced aggregation responses are largely unaffected by disruption of the P-12LO gene. Agonist was added to PRP as indicated by the arrow. Extent of aggregation of P-12LO−/− mouse platelets was not significantly different from wild-type control mouse platelets stimulated with γ thrombin (10–100 nM), collagen (2–40 μg/ml), U46619 (0.5–20 μM), or arachidonic acid (20–100 μM) (n = 4 to 6).