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. 2003 Feb 15;17(4):516–528. doi: 10.1101/gad.1044503

Figure 8.

Figure 8

HSF1 redox activation protects cells from stress-induced apoptosis. Hsf1−/− stable cell lines harboring the empty vector (V), wild-type HSF1 (WT), or the indicated mutant derivatives were incubated under control conditions (37°C), exposed to heat shock (44°C for 1 h followed by 6 h at 37°C), or 500 μM H2O2 at 37°C for 6 h. Relative apoptosis of these cultures was determined as described in Materials and Methods and plotted on the y axis as the Relative Apoptosis index.