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. Author manuscript; available in PMC: 2007 Aug 16.
Published in final edited form as: Adv Drug Deliv Rev. 2007 Apr 14;59(4-5):292–307. doi: 10.1016/j.addr.2007.03.017

Figure 2.

Figure 2

A) Viral and non-viral vectors can interact with polymeric biomaterials through non-specific mechanisms, including hydrophobic, electrostatic, and van der Waals interactions, and more specific interactions, regulated by avidin/biotin or antibody/antigen interactions. B) An immobilized vector can be released by desorption for non-specifically immobilized complexes, or covalently coupled vectors may require degradation of either the tether or the biomaterial for release.