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p16 and p21 protein expression in proliferating and senescent HDFs. Total extracts from the same number of cells from NHF1 (lanes 1 and 2), MRC-5 (lanes 3 and 4), IMR-90 (lanes 5 and 6), and WI-38 (lanes 7 and 8) strains of HDFs were analyzed for expression of p16 (A) and p21 (B) under conditions of log phase growth (lanes 1, 3, 5, and 7) and senescence (lanes 2, 4, 6, and 8).
