Table 3.
Discriminators of BCG effects versus TNF and LPS over time.
| Analyte | p value |
| GM-CSF | 0.001 |
| IL-1 beta | 0.007 |
| IL-2 | 0.006 |
| IL-3 | 0.032 |
| IL-4 | 0.016 |
| IL-6 | 0.000 |
| IL-10 | 0.001 |
| IL-12p70 | 0.012 |
| IL-17 | 0.002 |
| KC | 0.018 |
| RANTES* | 0.001 |
Urinary cytokines response over time was determined using a mixed modeling approach, according to the following equation: Cytokine Level = (a) * Time + (b) Trx * Time, where Trx is BCG vs LPS & TNF-Alpha. A variance component covariance matrix was used to account for the correlation structure inherent in longitudinal measurements of cytokines.*Time squared interaction.