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. 2002 Dec;12(12):1889–1900. doi: 10.1101/gr.327702

Table 1.

Number of Reactions Involved in the Production of the Indicated Target Product

H. pylori Target product Essential reactions Utilized reactions
Tryptophan 32 105
Tyrosine 28 101
Cysteine 25 102
Glycine 22 97
Lysine 22 102
Serine 16 91
Threonine 14 96
Asparagine 13 91
Aspartic Acid 12 91
Proline 10 91
Glutamic Acid 7 91
Glutamine 6 91
Equimolar Amino Acids 85 140
E. coli Ratio Amino Acids 85 140
H. influenzae Target product Essential reactions Utilized reactions
Histidine 51 112
Tryptophan 41 108
Phenylalanine 36 108
Tyrosine 36 108
Methionine 34 106
Isoleucine 31 108
Lysine 31 108
Glycine 29 82
Threonine 26 103
Asparagine 25 98
Serine 25 97
Leucine 23 105
Aspartic Acid 22 97
Glutamine 21 102
Proline 18 103
Valine 17 102
Alanine 12 99

See Fig. 3 for the indicated network inputs and outputs. Essential reactions refers to the number of reactions that were used in every extreme pathway (region I in Fig. 4). Utilized reactions refers to the number of reactions that were used at least once in the set of extreme pathways for the production of the associated product (region II in Fig. 4). The individual amino acids are sorted in descending order according to the number of essential reactions. Equimolar amino acids refers to the set of amino acids in equimolar ratios. E. coli ratio amino acids refers to the set of amino acids in ratios analogous to those seen in E. coli biomass.