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. Author manuscript; available in PMC: 2008 Apr 1.
Published in final edited form as: Clin Immunol. 2006 Dec 19;123(1):18–29. doi: 10.1016/j.clim.2006.10.014

Figure 3. Phenotypic analysis of transient FOXP3+ regulatory T cells.

Figure 3

a, Allostimulated, CFSE-stained CD4+CD25− T-cells were phenotyped for FOXP3, CD25, CTLA-4, CD27, CD62L, CCR7 and CD28 expression at day 6 of culture. Dividing CFSElow cells were positive for most of the markers shown, similar to the phenotype of ex vivo-purified Tregs. b, CD127 (IL7-R) expression was monitored on allostimulated T-cells, revealing CD127 downregulation with the induction of FOXP3. CD127 remained low at a point where FOXP3 was downregulated.