Table 4.
Correlation of CIMP Status and Clinicopathological Features of Sporadic Serrated Adenomas
| Characteristics | Total (no.) | CIMP-negative (n = 3) % (no.) | CIMP-low (n = 4) % (no.) | CIMP-high (n = 15) % (no.) | P value |
|---|---|---|---|---|---|
| Age ± SD (years) | 64 ± 12 | 59 ± 9 | 61 ± 7 | 66 ± 13 | NS |
| Gender | |||||
| Male | 13 | 15% (2) | 23% (3) | 62% (8) | NS |
| Female | 9 | 11% (1) | 11% (1) | 78% (7) | |
| Site | |||||
| Right colon | 10 | 0% (0) | 30% (3) | 70% (7) | NS |
| Left colon | 11 | 27% (3) | 9% (1) | 64% (7) | |
| Size | |||||
| ≤1.0 cm | 18 | 17% (3) | 22% (4) | 61% (11) | NS |
| >1.0 cm | 4 | 0% (0) | 0% (0) | 100% (4) | |
| History of hyperplastic polyps | |||||
| Present | 12 | 0% (0) | 22% (3) | 56% (9) | NS |
| Absent | 10 | 30% (3) | 10% (1) | 60% (6) | |
| History of conventional adenomas | |||||
| Present | 11 | 9% (1) | 36% (4) | 55% (6) | 0.04 |
| Absent | 11 | 18% (2) | 0% (0) | 82% (9) | |
| History of colorectal cancers | |||||
| Present | 6 | 0% (0) | 33% (2) | 67% (4) | NS |
| Absent | 16 | 19% (3) | 13% (2) | 69% (11) |