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Vimentin expression in HER2/neu-negative and -positive breast cancer cell lines and carcinomas. Immunohistochemical stains of cell lines MDA-MB-468 (A) and SKBR3 (B) as well as a HER2/neu-negative (C) and -positive (D) primary breast carcinoma. There is strong cytoplasmic reactivity in the HER2/neu-negative breast cancer cells (A, C) but absence of reactivity in the HER2/neu-positive tumor cells (B, D). Original magnifications, ×400.
