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. 2007 Jan 22;51(4):1386–1397. doi: 10.1128/AAC.01302-06

TABLE 2.

Antiviral activities of CCR5 mAbsa

Assay Avg IC50 (μg/ml) ± SD
2D7 ROAb10 ROAb13 ROAb18 ROAb14 ROAb12 ROAb36 ROAb51
CCF 0.73 ± 0.18 1.62 ± 0.54 2.10 ± 0.67 0.33 ± 0.13 0.20 ± 0.07 0.51 ± 0.14 23.6 ± 5.29 0.86 ± 0.20
Single-cycle antiviral 1.7 ± 0.57 1.74 ± 0.64 4.33 ± 1.7 0.17 ± 0.03 0.16 ± 0.04 0.18 ± 0.04 17.2 ± 4.37 0.73 ± 0.17
PBMC antiviral 0.34 ± 0.08 0.52 ± 0.12 0.03 ± 0.03 0.02 ± 0.01 0.02 ± 0.02 0.04 ± 0.03 4.6 ± 0.77 0.29 ± 0.09
a

Data are averages and standard errors from two or more independent experiments.