FIGURE 4.
Identification of two GlyR subpopulations within a gephyrin cluster. (A) Examples of trajectories for a “stable” (upper trajectory, circle) and a “swapping” GlyR (bottom trajectory, triangle); (gray) parts inside VeGe(2) clusters (dark gray). (B, C) Cumulative probability of diffusion coefficients inside VeGe(2) clusters for “stable” (circle) and “swapping” (triangle) GlyR in HeLa cells (B) and neurons (C). “Swapping” GlyRs diffuse faster than “stable” GlyRs (Kolmogorov-Smirnov test: HeLa cells, p-value < 0.01; neurons, p-value < 0.05). (inset) Vertical bars give the confinement diameter (dconf, mean ± SE) for trajectories showing a restricted motion.