Figure 3.
Histopathological effects induced by overexpression of AdTNF-α at various time points. A, B, C, and E are stained with hematoxylin and eosin; D is stained with Elastic van Gieson (collagen stained red and elastin black). Cells are shown on day 3 (A), day 7 (B), day 14 (C and D), and day 64 (E) after infection. Magnifications: ×160 (A, B, and E) and ×250 (C and D). Arrows show fibrogenic response in the interstitium. Arrowhead shows patchy scarring and distorted architecture in the interstitium. b, bronchial structure; v, vascular structure.