Table 2.
Loss of Heterozygosity Results for Individual Chromosome 16p13 Markers
| Patient | Tissue | D16S749 | D16S287 | D16S418 | D16S291 | Kg8 |
|---|---|---|---|---|---|---|
| 436 | Angiomyolipoma* | —† | LOH‡ | LOH | LOH | LOH |
| Smooth muscle cells | — | LOH | LOH | LOH | LOH | |
| Adipose tissue | — | LOH | LOH | LOH | LOH | |
| Cellular vessels | — | LOH | LOH | LOH | LOH | |
| Hemangiopericytic vessels | — | LOH | LOH | LOH | LOH | |
| Glomeruloid vessels | — | — | — | — | — | |
| Aneurysmatic vessels | — | — | — | — | — | |
| Collagenous vessels | — | 2§ | 2 | 2 | 2 | |
| 437 | Angiomyolipoma* | 2 | 2 | 2 | LOH | LOH |
| Smooth muscle cells | 2 | 2 | 2 | LOH | LOH | |
| Adipose tissue | — | — | — | — | — | |
| Cellular vessels | 2 | 2 | 2 | LOH | LOH | |
| Hemangiopericytic vessels | 2 | 2 | 2 | LOH | LOH | |
| Glomeruloid vessels | 2 | 2 | 2 | LOH | LOH | |
| Aneurysmatic vessels | — | — | — | — | — | |
| Collagenous vessels | 2 | 2 | 2 | 2 | 2 | |
| Endothelial cells | — | — | — | 2 | 2 | |
| 487 | Angiomyolipoma* | LOH | 1¶ | LOH | 1 | LOH |
| Smooth muscle cells | LOH | 1 | LOH | 1 | LOH | |
| Adipose tissue | — | — | — | — | — | |
| Cellular vessels | LOH | 1 | LOH | 1 | LOH | |
| Hemangiopericytic vessels | — | — | — | — | — | |
| Glomeruloid vessels | — | — | — | — | — | |
| Aneurysmatic vessels | LOH | 1 | LOH | 1 | LOH | |
| Collagenous vessels | — | — | — | — | — | |
| 492 | Angiomyolipoma* | — | 2 | LOH | LOH | 1 |
| Smooth muscle cells | — | — | — | — | — | |
| Adipose tissue | — | 2 | LOH | LOH | 1 | |
| Cellular vessels | — | — | — | — | — | |
| Hemangiopericytic vessels | — | 2 | LOH | LOH | 1 | |
| Glomeruloid vessels | — | 2 | LOH | LOH | 1 | |
| Aneurysmatic vessels | — | 2 | LOH | LOH | 1 | |
| Collagenous vessels | — | 2 | 2 | 2 | 1 |
*Non-microdissected tissue;
†vessels of this type not present in this case, or this marker not typed for this patients;
‡LOH: loss of heterozygosity;
§2: retention of heterozygosity;
¶1: non-informative marker.
The markers are listed in centromeric to telomeric order.