TABLE 2.
Specific oxidation index of DJ-1 isoforms in PD, AD, and control brains. The specific oxidation index was obtained by normalization of the intensity of the carbonyl level to the intensity of protein level of the indicated DJ-1 isoform. Values represent the mean ± S.E. for five individuals of each of the PD, AD, or control group.
| DJ-1 isoform (Mr/pI) | Control | PD | AD |
|---|---|---|---|
| n = 5 | n = 5 | n = 5 | |
| 20/pI 6.4 | 0.30 ± 0.03 | 1.17 ± 0.23a | 1.07 ± 0.30a |
| 39/pI 7.4 | 0.43 ± 0.06 | 1.93 ± 0.50a | 2.06 ± 0.60a |
| 39/pI 8.0 | 0.73 ± 0.17 | 1.63 ± 0.26a | 1.67 ± 0.30a |
| 39/pI 8.4 | 0.97 ± 0.13 | 4.00 ± 0.40a | 3.66 ± 0.60a |
p < 0.05.