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. Author manuscript; available in PMC: 2007 Mar 26.
Published in final edited form as: Mol Cell Endocrinol. 2006 Oct 19;260-262:137–143. doi: 10.1016/j.mce.2005.09.015

Fig. 2.

Fig. 2

Hypothetical models of trans-activation and cis-activation. (A) The exodomain complexed with hormone intramolecularly modulates its own endodomain (cis-activation), and (B) intermolecularly modulates unoccupied receptor (trans-activation).