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. 2007 Feb 9;104(8):2602–2607. doi: 10.1073/pnas.0611213104

Table 1.

IC50 values for pools of compounds screened against LC/A (1–425)

Compounds Pool size IC50, μM
29A7 (BBF-AB11C7)* 10 14.8
5G7 (HD1c-A1B7Cm2)† 8 16.9
14E2 (FA-A2B2C) 3 15.8
39G6 (TransPyr1-A1B6Cm1) 10 13.0
40D9 (TransPyr1-A6B9Cm1) 10 19.3
40H6 (TransPyr1-A10B6Cm1) 10 19.8
42F6 (TransPyr1-A4B6Cm3) 10 16.2
43C7 (TransPyr1-A9B7Cm3) 10 11.1

Assays were conducted at varied concentration of the pooled inhibitors at 23°C, pH 7.4, in 40 mM Hepes, 5 μM SNAPtide, and 7 nM LC/A.

*See ref. 47 for library preparation.

†See ref. 48 for library preparation.