Table 2.
Phenotypic expression analysis of circulating CD4+ CD25+ T cells in patients with normal and elevated alanine aminotransferase (ALT) as determined by flow cytometry.
| CD4+ CD25+ phenotype | Normal ALT | Elevated ALT | Note* |
|---|---|---|---|
| CD45RO+ | 75 ± 12 | 77 ± 10 | n.s. |
| CD45RA+ | 19 ± 4 | 22 ± 4 | n.s. |
| CD27+ | 79 ± 9 | 83 ± 7 | n.s. |
| CD28+ | 83 ± 7 | 80 ± 9 | n.s. |
| CD95+ | 73 ± 10 | 70 ± 6 | n.s. |
| CD69+ | 1·2 ± 0·2 | 1·4 ± 0·1 | n.s. |
Peripheral blood mononuclear cells (PBMC) from patients with normal ALT levels and elevated ALT were stained with fluorochrome-labelled CD4, CD25, CD45RO, CD45RA, CD27, CD28, CD95 and CD69 surface molecules. Isotype antibodies served as controls;
*
n.s. = not significant.