Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
ITC titration of a model 1:1 interaction: the binding of CBS to CAII. (A) Raw measured heat changes as a function of time, injecting 720 μM CBS into 35 μM CAII at 25°C. (B) Normalized measured heats of injection (circles), best-fit values (solid line). Parameter estimates were K = 1.22 × 106/M and ΔH = −10.65 kcal/mol, f CAII = 0.012, baseline = −0.143 kcal/mol. (C) Residuals of the fit with a RMSD of 0.050 kcal/mol.
