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. Author manuscript; available in PMC: 2007 Jan 4.
Published in final edited form as: Endocr Pract. 2006;12(Suppl 1):20–24. doi: 10.4158/EP.12.S1.20

Table 1.

Cumulative Risk of Developing Diabetes and Effect of Interventions in Diabetes Prevention Program

Factor Placebo Metformin Lifestyle
Incidence of diabetes (% per year) 11.0 7.8 4.8
Reduction in incidence compared with placebo (%) … 31 58
Number needed to treat to prevent 1 case in 3 years … 13.9 6.9

Adapted from Knowler et al (Diabetes Prevention Program Research Group) (3).