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The 19-kDa lipoprotein does not induce apoptosis in THP-1 cells. Apoptosis was measured in THP-1 cells (106 cells/ml) either cultured in medium alone or treated with 19-kDa lipoprotein (500 ng/ml) for 24 h. After the 24-h incubation, cells were fixed in 2% paraformaldehyde and DNA fragmentation was measured by TUNEL assay. DNase I served as a positive control.
